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Early-stage diagnostic study

Polyp study

This medical study aims to identify markers in your blood or stool that can improve how we find and diagnose colorectal polyps and bowel cancer.

  • Scheduled for a colonoscopy


​Australia-wide - this trial can be completed from the comfort of your own home at no cost to you!


​Up to 3 months

Man Doing Blood Test
If you take part in the research study, there will be:
Flexibility and Convenience

The trial can be completed from the comfort of your own home at no cost to you!


Contribute to research that may help to improve the way we find and diagnose colorectal polyps and bowel cancer.

Study Guide


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Who can take part in this study?
In order to be eligible to participate in the study, you must meet all of the following:
  • You are scheduled to have a routine colonoscopy due to:

    • Positive bowel cancer screening test result (FIT test);​

    • Routine screening/follow-up after previous colorectal neoplasia diagnosis in the past 10 years;

    • Routine screening/follow-up due to family history of colorectal neoplasia or cancer; or

    • Investigating symptoms

  • Aged over 18 years old

  • Reside in Australia with access to the internet and with a postage address

  • Physically capable to self-collect blood and stool biospecimens


Who is unable to take part in this study?
Unfortunately, if you meet any of the following, this study is not the right fit for you:
  • Anyone who is scheduled to have a routine colonoscopy for reasons such as inflammatory bowel disease;

  • Anyone who has had part of their bowel surgically removed;

  • Anyone diagnosed with any of the following chronic gastrointestinal conditions:

    • Inflammatory bowel disease (IBD)​

    • Ulcerative colitis

    • Active diverticulitis in the prior 2 months

  • Anyone diagnosed with an genetic colorectal conditions including Lynch Syndrome (HNPCC) or Familial Adenomatous Polyposis (FAP)


How long with the study take?


If you agree to take part, and the study is suitable for you, your participation in the study is expected to last up to 3 months. This includes:

The collection of a small volume blood sample from a finger prick, and a stool sample.


Both samples will be collected at-home and posted back to the study investigators for analysis - you will be shipped a study kit at no cost to you and provided with a return-paid envelope to post back the blood and stool samples.


Most participants will only be required to provide samples at one time point prior to the colonoscopy, however a group of participants will be asked to provide additional samples at 2-months post-colonoscopy.


Researchers will also ask that you provide the results of your colonoscopy as well as other information regarding your medical history that is relevant to the study.

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What is the purpose of this study?


This study aims to investigate if there are any biological markers (biomarkers) in blood or stool that can be used to determine if you have a colorectal polyp. The identification of these markers can leads to improved diagnostics and the ability to accurately track and monitor disease and treatment options.


What are colorectal polyps?


A colon polyp is a small clump of cells that forms on the lining of the colon. Although most colon polyps are harmless, over time, some colon polyps may become cancerous. Colon polyps don't usually cause any symptoms, so it is important to have regular screening tests. If found in the early stages, they can usually be removed safely and effectively. The best prevention for colon cancer is regular screening for, and removal of polyps.


Anyone can develop polyps, however people who are aged 50 years or older, are overweight, or have a history of smoking are at a higher risk. Additionally, family history of colon polyps or colon cancer also puts you at a higher risk of developing colon polyps.


What if I have other questions about the study?


We are here for you! Click or tap this button to send an email to our trials team:

Help make medical research breakthroughs happen.

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